10 Things You didn’t know about Queen Victoria
Born as Princess Alexandrina Victoria on May 24, 1819, Queen Victoria was a British monarch who ruled from 1837 to 1901. At the height of her reign, Victoria was undoubtedly...
Hemophilia is a rare, inherited bleeding disorder in which the blood does not clot properly. The condition is primarily caused by mutations in genes responsible for producing proteins that play a critical role in blood coagulation. Understanding the genetics of hemophilia provides insights into its diagnosis, treatment, and inheritance patterns.
There are two primary types of hemophilia: Hemophilia A and Hemophilia B. Each type is linked to a mutation in a specific gene:
Hemophilia follows an X-linked recessive inheritance pattern. This means:
The severity of hemophilia (mild, moderate, or severe) largely depends on the level of functional clotting proteins produced by the body. Severe hemophilia often leads to spontaneous bleeding episodes, whereas milder forms may only cause bleeding after trauma or surgery.
Modern advancements have made it possible to produce synthetic clotting factors, which are administered to patients to help manage and prevent bleeding episodes.
Born as Princess Alexandrina Victoria on May 24, 1819, Queen Victoria was a British monarch who ruled from 1837 to 1901. At the height of her reign, Victoria was undoubtedly...